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Woman getting pregnant by bone marrow

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Researchers found that when an egg is fertilised, stem cells leave the bone marrow and travel via the bloodstream to the uterus, where they help transform the uterine lining for implantation. If the lining fails to go through this essential transformation, the embryo cannot implant, and the body terminates the pregnancy. Study first author Dr. Using mice, researchers found that a bone marrow transplant from a healthy donor could improve fertility.

SEE VIDEO BY TOPIC: Bone Marrow Transplant Anniversary - The Nebraska Medical Center

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SEE VIDEO BY TOPIC: Scientists Make Sperm Out Of Two Women's Skin!

Bone marrow stem cells may be vital for pregnancy

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Credit: Getty Images. The study shows that when an egg is fertilized, stem cells leave the bone marrow and travel via the bloodstream to the uterus, where they help transform the uterine lining for implantation.

If the lining fails to go through this essential transformation, the embryo cannot implant, and the body terminates the pregnancy. But knowing that bone marrow has a significant role is a paradigm shift. In this study, the researchers were able to prove the physiological relevance of stem cells to pregnancy. In two mouse models with the Hoxa11 gene defect, which presents in mice as a defective endometrium, the researchers found that a bone marrow transplant from a healthy donor could improve fertility by promoting sufficient decidualization of the endometrium.

In mice with only one copy of the defective gene, the transplant saved pregnancies that would otherwise have been lost and increased litter sizes, while in the mice with two bad copies of the gene, which were thus entirely infertile, the transplant caused growth and repair of the defective endometria. This study was possible due to a methods breakthrough that Tal and Taylor made a few years ago.

Before a bone marrow transplant , chemotherapy or radiation clears the body of the existing bone marrow, so that the donor bone marrow can take its place. Though more research is needed prior to clinical trials, Tal and Taylor see hope for the patients they treat for infertility on the clinical side of their practice in this latest advance. Bone marrow can be considered another critical reproductive organ. This finding opens up a new potential avenue for treatment of a condition that has been untreatable in the past.

Leet and Clara Guthrie Patterson Fellowship funded the research. Source: Yale University. Search for:. Science Health Culture Environment. Share this Article. You are free to share this article under the Attribution 4. High blood pressure in pregnancy has spiked since Stay Connected. Subscribe to our Newsletter. Add your information below to receive daily updates. Sign Up. Older Posts. First Name. This field is for validation purposes and should be left unchanged.

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Bone marrow-derived cells play a role in changes to the mouse uterus before and during pregnancy, enabling implantation of the embryo and reducing pregnancy loss, according to research published September 12 in the open-access journal PLOS Biology. Although the study was done in mice, it raises the possibility that dysfunction of bone marrow-derived progenitor cells may contribute to implantation failure and pregnancy loss in women. Bone marrow progenitors can become either blood or tissue cells. Within the uterus they differentiate into endometrial tissue cells in the lining of the womb, but until now it was not known if they have a function in pregnancy.

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Catch up on stories from the past week and beyond at the Slashdot story archive. I guess after being told to "Go Fuck Yourself" for so many years, these scientists finally found a way to do it. There will be some interesting debates raging about this one for a long time. I'm of the opinion that on the whole, we are better off with the process of gene mixing than practicing self-eugenics.

Bone stem cells turned into primitive sperm cells

Stem cells have generated such an enormous amount of interest, in part, because of their applications related to areas such as fertility and genetics. In that same light, their interest for solving reproductive challenges has also generated a great deal of controversy. This is particularly true in the application of stem cells to facilitate reproduction for gay couples. At present, there are a number of research laboratories that are focused on the creation of cells that are genetically male but have been produced from eggs. Alternately, they are also trying to create sperm from female eggs. If the research proves to work, the consequences are particularly important for gay and lesbian couples that wish to have children. The idea is, however, an extremely controversial one that mixes in with politics, religion and ethics. Many individuals oppose same-sex reproduction while gay and lesbian couples - as well as heterosexual members of the public - argue that gay persons should have the right to produce and raise biological children if the opportunity becomes available. Current Research for Same Sex Reproduction The techniques purported to allow same-sex reproduction have yet to be successful but they do hold promise.

Bone marrow may be the missing piece of the fertility puzzle

Log in Advanced Search. A study in mice suggests that bone marrow-derived stem cells may play a role in establishing pregnancy. The research showed that the stem cells can travel through blood circulation to the uterus, making it more receptive for a new embryo. Specifically, the authors showed that these cells concentrate in the lining of the uterus where the embryo is about to implant.

By Roxanne Khamsi. In a first step towards creating artificial sperm cells, researchers have turned human bone marrow tissue into primitive sperm cells.

But recently a team of scientists announced they had made artificial sperm from human bone marrow , and media reports abounded with the dire news that my goodfellas and by extension, me had been rendered unnecessary. There are at least half a dozen reasons why such speculation is silly, some scientific and some practical. For example, as long as sex feels good and remains no more expensive than dinner and a bottle of wine, most people will use natural-grown sperm.

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Bone marrow failure diseases frequently occur in women who are young and of child bearing age. People with these diseases have legitimate concerns about whether a pregnancy will cause their infants to suffer from the disease or its treatment, or whether their own disease will relapse. But the goal of modern therapy and modern obstetrics is to minimize both maternal and fetal complications.

SEE VIDEO BY TOPIC: Parent's conceive baby for bone marrow transplant for sick sibling - 60 Minutes Australia

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How bone marrow boosts chances of a healthy pregnancy

It may be hard to get and stay pregnant for some would-be mums, but there is hope. Scientists have discovered the vital role bone marrow plays in pregnancy, which can lead to new therapies in the future. In 10 seconds? Stem cells play a key role in successful pregnancies. Read the science. What exactly was discovered? Stem cells arriving from the bone marrow to the uterus transform its lining and help the implantation of the embryo by becoming decidual cells essential for getting and staying pregnant.

Oct 15, - It may be hard to get and stay pregnant for some would-be mums, but the bone marrow to the uterus via the bloodstream when a woman's.

Since the late s, scientists have explored how to produce sperm where all of the chromosomes come from a female donor. Creating female sperm was first raised as a possibility in a patent filed in [3] by injecting a woman's cells into a man's testicles, though the patent focused mostly on injecting altered male cells into a man's testes to correct genetic diseases. In , Japanese scientists partially confirmed such techniques by creating chicken female sperm in a similar manner.

Pregnancy following Bone Marrow Transplant

The breakthrough paves the way for lesbian couples to have children that are biologically their own. Researchers at Newcastle upon Tyne University say their technique will help lead to new treatments for infertility. But critics warn that it sidelines men and raises the prospect of babies being born through entirely artificial means.

Cells that make bone marrow also travel to the womb to help pregnancy

Credit: Getty Images. The study shows that when an egg is fertilized, stem cells leave the bone marrow and travel via the bloodstream to the uterus, where they help transform the uterine lining for implantation. If the lining fails to go through this essential transformation, the embryo cannot implant, and the body terminates the pregnancy.

The study shows that when an egg is fertilized, stem cells leave the bone marrow and travel via the bloodstream to the uterus, where they help transform the uterine lining for implantation.

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